The Jerusalem Post reports that doctors at Haifa's Rambam Health Care Campus "have successfully treated their first Israeli opioid addiction patient using an experimental noninvasive brain technology, easing him through withdrawal in just 20 minutes..." [T]he team of specialists at the Haifa medical center intervened in the electrical activity of an area of the patient's brain called the nucleus accumbens, the core of the brain system responsible for feelings of satisfaction, pleasure, and reward. The treatment, based on technology from the Israeli company Insightec, is similar to the one used to treat symptoms of essential tremor and Parkinsonian tremor, under MRI control. In this case, the treatment was carried out with the help of a new technology that performs noninvasive neuromodulation, without heating or burning tissue, and allows stimulation in the same area of the brain to increase or suppress activity... "Tests carried out a week later produced negative results for opioids and other substances," [said Dr. Lior Lev-Tov, director of the functional neurosurgery unit in Rambam's neurosurgery division and the one leading the new study at the medical center.] "The patient himself reported a craving score of zero out of 10 for using the drug, and even another side effect, a drastic drop in the desire for cigarettes, from three packs a day to just a few cigarettes, and with no urge to use alcohol. In other words, in a treatment that lasted about 20 minutes net, our patient was completely freed from an extreme dependence that had accompanied him every day for years. This is nothing less than a medical and therapeutic revolution." Dr. Lev-Tov added that "This experience opens doors for us to treat a wide range of very serious illnesses such as PTSD, OCD, eating disorders, other addictions, severe depression, severe pain disorders, and I hope we will also be able to reach cognitive areas and treat attention deficit disorders, Alzheimer's, Parkinson's, and more." Thanks to Slashdot reader Bruce66423 for sharing the article.

Read more of this story at Slashdot.

An anonymous reader quotes a report from MIT Technology Review: [T]he payment company Stripe, founded by brothers Patrick and John Collison, says it will fund a new $500 million nonprofit whose goal is preventing both the common cold and the flu. Its eventual aim is to get rid of respiratory viruses altogether. The new organization, called Intercept, will use grants and investments to back prevention approaches, including vaccines, as well as large-scale air-cleaning systems for schools, offices, and other public spaces. In addition to Stripe, other funders include Anthropic, Flu Lab, and the OpenAI Foundation, as well as Bill Gates and several traders at the quantitative investing fund Jane Street Capital, according to an Intercept spokesperson. "I think we treat respiratory infections as a minor nuisance, but have really underweighted the burden that they impose on society," says Nan Ransohoff, the Stripe executive leading the initiative along with Charlie Petty, a venture capitalist who joined Stripe this year. On average, people spend 5% of their lifetime fighting a cold or the flu, according to Ransohoff. Despite that, drug companies put relatively little effort into preventing colds. Part of the problem is that the sniffles are caused by more than 200 different viruses, according to the American Lung Association, with rhinoviruses being the most common culprits. There are so many that it typically doesn't pay to try to stop any one of them with a vaccine. "When pharma companies look at it, it's not as attractive as other things they could work on," says Ransohoff. "So it hasn't attracted the resources." [...] The project takes inspiration from efforts to fight the covid-19 virus, where Veesler's group was among those involved in the speedy development of vaccines, antiviral drugs, and antibodies. According to Ransohoff, Intercept's advisors will include Peter Marks, a former top FDA official, as well as Moncef Slaoui, the pharmaceutical executive who led the US coronavirus vaccine effort, Operation Warp Speed. A key challenge for Intercept will be coming up with ways to counter many viruses at one time. That accounts for the interest in air-cleaning technology, such as using strong ultraviolet light to inactivate viruses. The idea, the group says, is to remove them from the air in the same way municipalities remove impurities from the water supply before it's piped to people's homes.

Read more of this story at Slashdot.

UC Davis researchers say an implanted brain-computer interface has allowed Casey Harrell, an ALS patient who cannot speak, to synthesize sentences from brain activity with 99% accuracy in controlled tests and about 92% accuracy in everyday use. The Register reports that the system has remained usable at home since 2023, helping Harrell communicate naturally, control a computer, and return to full-time work without researchers needing to supervise each session. The Register reports: A team of scientists from the University of California, Davis, published a paper Monday detailing a years-long study of a brain computer interface (BCI) system implanted in a patient with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), which destroys motor neurons and causes loss of motor control and eventual paralysis. According to the team, their patient, Casey Harrell, has been living with BCI implants since 2023 that are still working today, giving him the ability not only to control a computer cursor with his thoughts, but also to speak. [...] Davis neurosurgeon David Brandman, co-principal investigator and co-senior author of the paper published Monday, as well as the surgeon who placed Harrell's implant, described the results his team published as the crossing of a threshold in BCI technology: Not only has Harrell's implant been working well with daily use since 2023, but it's also incredibly accurate. In controlled tests, the system managed to synthesize sentences from Harrell's brain activity with 99 percent accuracy; outside of the lab in daily use, Harrell still assessed it as being accurate 92 percent of the time. "The key thing to me is that it's enabling everyday communication for a guy who wants to talk but can't," Brandman told The Register in an interview. "Despite being paralyzed [Harrell] has gone back to work full time and has meaningful conversations with his daughter who's never heard the sound of his voice." Prior work in the BCI space, Brandman told us, has either required researchers to be in a patient's home whenever they're using the tech, or for the patient to come to the researchers. That's not the case here, with the system allowing Harrell's home care team to hook him up to the system themselves, enabling him to use the device for more than 3,800 hours in the past few years. Based on the time the study was filed (It published Monday but went into peer review in July 2025) that would mean Harrell was using the device for more than five hours a day, on average. "It is a life that is more full of dynamic action and with friends and family, with colleagues, and it is something that allows me to communicate more in my natural way of communicating than any other technology that I have experienced," Harrell told UC Davis via his BCI system.

Read more of this story at Slashdot.